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Effect of Testosterone Replacement Therapy on Prostate Tissue in Men With
Late-Onset Hypogonadism: A Randomized Controlled Trial |
However, when aging men receive testosterone, the potential effects of the male hormone on the prostate gland are a paramount concern. Aging men have a substantial prevalence of subclinical prostate disease, both benign and malignant, and testosterone is the primary nutrient for the prostate. Thus, a fear about the prostatic effects of TRT has been present for decades. While several studies have failed to show any overt effects clinically, none has focused on prostate tissues. In 2001 the USRF team began such an investigation. The result of that 5-year work, "Effects of Testosterone Replacement Therapy on Prostate Tissues in Men with Late Onset Hypogonadism," was published in a special Men's Health issue of J.A.M.A. in November, 2006.
The JAMA Men’s Health Issue (Nov. 15, 2006) was launched with a press conference in New York City on Nov. 14, 2006. At the conference, JAMA editor Katherine DeAngelis introduced the 4 invited speakers, each of whom contributed an original research paper to the issue. In addition to the USRF article, a number of other practice-changing studies were featured, leading to substantial coverage of the Men’s Health Issue in the lay press. Jim’s
Story
Co-authors
of TRT paper in JAMA History of Testosterone Replacement Therapy (TRT) |
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This posting and overall website maintenance by
Anthony Cancio
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