Slide 10 of 18

Since prostate volume is reflected in serum PSA levels (assuming cancer has been excluded), the PSA test can be used to help define risk in individual patients. In this example, a 50 year old man with a PSA of 4.0 ng/ml would be expected to have a prostate volume of approximately 45 cc; if that man were 75 y.o, he would be expected to have a prostate volume of 55 cc. Prostate volume and age are the primary determinants of serum PSA levels, under normal conditions.